Abstract
Upper Airway Resistance Syndrome (UARS) was initially used to describe a group of patients who were sleepy but did not meet the diagnostic criteria of obstructive sleep apnea syndrome (OSAS). Since the original description, controversy and ambiguity of this disorder have lead to limited amounts of adequate data and studies. The incidence, prevalence, natural history, and morbidity of this disorder are not well known, and the diagnosis of UARS remains a controversial issue. Advances in technology have lead to measurement of sensitive polysomnographic variables that may aid in effectively identifying this disorder, distinguishing it from OSAS. Recognition of patients with UARS is important because although these patients are symptomatic, they may not present with the same symptoms as patients with OSAS. Treatment options are available that may benefit patients with UARS. This article reviews the pathophysiology, diagnosis, clinical picture and management of UARS.
Keywords: obstructive sleep apnea syndrome, airway pressure, EEG pattern, continuous positive airway pressure, NREM sleep
Current Respiratory Medicine Reviews
Title: Upper Airway Resistance Syndrome
Volume: 4 Issue: 1
Author(s): Christian Guilleminault and Kannan Ramar
Affiliation:
Keywords: obstructive sleep apnea syndrome, airway pressure, EEG pattern, continuous positive airway pressure, NREM sleep
Abstract: Upper Airway Resistance Syndrome (UARS) was initially used to describe a group of patients who were sleepy but did not meet the diagnostic criteria of obstructive sleep apnea syndrome (OSAS). Since the original description, controversy and ambiguity of this disorder have lead to limited amounts of adequate data and studies. The incidence, prevalence, natural history, and morbidity of this disorder are not well known, and the diagnosis of UARS remains a controversial issue. Advances in technology have lead to measurement of sensitive polysomnographic variables that may aid in effectively identifying this disorder, distinguishing it from OSAS. Recognition of patients with UARS is important because although these patients are symptomatic, they may not present with the same symptoms as patients with OSAS. Treatment options are available that may benefit patients with UARS. This article reviews the pathophysiology, diagnosis, clinical picture and management of UARS.
Export Options
About this article
Cite this article as:
Guilleminault Christian and Ramar Kannan, Upper Airway Resistance Syndrome, Current Respiratory Medicine Reviews 2008; 4 (1) . https://dx.doi.org/10.2174/157339808783497882
DOI https://dx.doi.org/10.2174/157339808783497882 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
A Pilot Study to Assess Adenosine 5’-triphosphate Metabolism in Red Blood Cells as a Drug Target for Potential Cardiovascular Protection
Cardiovascular & Hematological Disorders-Drug Targets Comparing the Molecular Pharmacology of CGRP and Adrenomedullin
Current Protein & Peptide Science Tumor Angiogenesis and VEGFR-2: Mechanism, Pathways and Current Biological Therapeutic Interventions
Current Drug Metabolism Ethanol Withdrawal and Hyperalgesia
Current Drug Abuse Reviews Pharmacological Properties and Therapeutic Possibilities for Drugs Acting Upon Endocannabinoid Receptors
Current Drug Targets - CNS & Neurological Disorders Endocannabinoid Signaling in the Etiology and Treatment of Major Depressive Illness
Current Pharmaceutical Design Hypertension in Obstructive Sleep Apnoea
Vascular Disease Prevention (Discontinued) Targeted Cancer Therapy: The Next Generation of Cancer Treatment
Current Drug Discovery Technologies Clinical Use of Rituximab in Patients with HIV Related Lymphoma and Multicentric Castlemans Disease
Current Drug Delivery Angiotensin-Converting Enzyme Inhibitors: Mechanisms of Action and Implications In Anesthesia Practice
Current Pharmaceutical Design Medications Affecting Functional Status in Older Persons
Current Pharmaceutical Design Enantiomeric Local Anesthetics: Can Ropivacaine and Levobupivacaine Improve Our Practice?
Current Drug Therapy Use of Push-Pull Superfusion Technique for Identifying Neurotransmitters Involved in Brain Functions: Achievements and Perspectives
Current Neuropharmacology A Role for Leptin in the Systemic Inflammatory Response Syndrome (SIRS) and in Immune Response, an Update
Current Medicinal Chemistry Ghrelin, A Novel Peptide Hormone in the Regulation of Energy Balance and Cardiovascular Function
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Acute Severe Arterial Hypertension: Therapeutic Options
Current Drug Targets Contribution and Value of Biomarkers in Acute Aortic Syndromes
Current Pharmaceutical Biotechnology Classical and New Renin-Angiotensin Signalling in Atherosclerosis
Current Signal Transduction Therapy Natural Alkaloids and Diabetes Mellitus: A Review
Endocrine, Metabolic & Immune Disorders - Drug Targets Direct and Indirect Antimicrobial Activities of Neuropeptides and their Therapeutic Potential
Current Protein & Peptide Science