Abstract
Virtual high-throughput screening (vHTS) is a powerful technique for identifying hit molecules as starting points for medicinal chemistry. Numerous successful applications of vHTS have been published using a large variety of methodologies. This review attempts to identify the essential factors for successful virtual screening in the hit identification phase.
Keywords: Virtual screening, high-throughput screening, docking, scoring, hit identification, similarity search
Mini-Reviews in Medicinal Chemistry
Title: Essential Factors for Successful Virtual Screening
Volume: 8 Issue: 1
Author(s): Markus H.J. Seifert and Martin Lang
Affiliation:
Keywords: Virtual screening, high-throughput screening, docking, scoring, hit identification, similarity search
Abstract: Virtual high-throughput screening (vHTS) is a powerful technique for identifying hit molecules as starting points for medicinal chemistry. Numerous successful applications of vHTS have been published using a large variety of methodologies. This review attempts to identify the essential factors for successful virtual screening in the hit identification phase.
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Cite this article as:
Seifert H.J. Markus and Lang Martin, Essential Factors for Successful Virtual Screening, Mini-Reviews in Medicinal Chemistry 2008; 8 (1) . https://dx.doi.org/10.2174/138955708783331540
DOI https://dx.doi.org/10.2174/138955708783331540 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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