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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Intriguing, Regioselective Synthesis of Novel 2-(1-Adamantylmethyl) tetrahydropyridines

Author(s): George B. Foscolos, Ioannis Papanastasiou and Andrew Tsotinis

Volume 5, Issue 1, 2008

Page: [57 - 59] Pages: 3

DOI: 10.2174/157017808783330117

Price: $65


Treatment of piperidine 8 with acetyl chloride or ethyl chloroformate in the presence of triethylamine gave the 2,3-dehydrogenated products 10a and 10b, respectively, together with the expected N-acylpiperidines 9.

Keywords: N-acyl adamantylmethylpiperidines, N-acyl adamantylmethyltetrahydropiperidines, synthesis

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