Abstract
Reaction of 2,4-diaryl-2,3-dihydro-1H-1,5-benzodiazepines 1 either with acetyl chloride in dry CH2Cl2 in the presence of pyridine, or with acetic anhydride in the presence or absence of base afforded, after unexpected opening of the benzodiazepine ring, N-butenylidene-amino-phenylacetamides 3 in excellent yields instead of the expected ring tautomers 2.
Keywords: 2,3-dihydro-1H-1, 5-benzodiazepines, acetylation, 2-N-butenylidene-amino-phenylacetamides, benzodiazepine ring opening, ring-chain tautomerism
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Carbohydrates: Synthesis, properties and applications
This special issue on carbohydrates will the first of a series focused on the biomolecules, the following ones being amino acids / peptides, nucleosides / nucleotides, lipids. All the issues of the series will contain exclusively full-length reviews and mini-reviews on the given topic written by specialists working in technologically ...read more
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