Abstract
Allergy prevalence has increased worldwide over the last 25 years along with industrialization and westernized lifestyles. Indoor allergens are primarily responsible for the sensitization and development of atopic diseases. The main indoor allergens are known to be derived from various arthropods which account for up to 80% of the kingdom Animalia. The two classes of arthropods are Insecta, which includes cockroaches, flies, mosquitoes, ants and silverfishes, and Arachnida, which includes mites, spiders, ticks, and scorpions and are the main sources of the allergens. Excreted materials, cast-overs from skin-molting, and dead debris are sources of allergens that can sensitize genetically predisposed individuals and elicit allergic disorders. The use of molecular biology techniques has contributed to the identification and characterization of an ever-increasing number of allergens. However, key determinants and allergen properties that drive allergic responses are poorly understood. The biological characterization of allergens will provide an understanding of the pathogenesis of allergic diseases and contribute to the development of new diagnostic and therapeutic approaches.
Keywords: Allergen, allergy, arthropod, asthma, atopy, insect
Protein & Peptide Letters
Title: Domestic Arthropods and Their Allergens
Volume: 14 Issue: 10
Author(s): Kyoung Yong Jeong, Chein-Soo Hong and Tai-Soon Yong
Affiliation:
Keywords: Allergen, allergy, arthropod, asthma, atopy, insect
Abstract: Allergy prevalence has increased worldwide over the last 25 years along with industrialization and westernized lifestyles. Indoor allergens are primarily responsible for the sensitization and development of atopic diseases. The main indoor allergens are known to be derived from various arthropods which account for up to 80% of the kingdom Animalia. The two classes of arthropods are Insecta, which includes cockroaches, flies, mosquitoes, ants and silverfishes, and Arachnida, which includes mites, spiders, ticks, and scorpions and are the main sources of the allergens. Excreted materials, cast-overs from skin-molting, and dead debris are sources of allergens that can sensitize genetically predisposed individuals and elicit allergic disorders. The use of molecular biology techniques has contributed to the identification and characterization of an ever-increasing number of allergens. However, key determinants and allergen properties that drive allergic responses are poorly understood. The biological characterization of allergens will provide an understanding of the pathogenesis of allergic diseases and contribute to the development of new diagnostic and therapeutic approaches.
Export Options
About this article
Cite this article as:
Jeong Yong Kyoung, Hong Chein-Soo and Yong Tai-Soon, Domestic Arthropods and Their Allergens, Protein & Peptide Letters 2007; 14 (10) . https://dx.doi.org/10.2174/092986607782541114
DOI https://dx.doi.org/10.2174/092986607782541114 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Radiosynthesis of 2-deoxy-2-[18F]fluorothymidine ([18F]FT), a Putative PET Agent for Imaging HSV-TK Expression
Current Radiopharmaceuticals The Antitumor Effects of Icaritin Against Breast Cancer is Related to Estrogen Receptors
Current Molecular Medicine Molecular Mechanisms Involved in the Aging of the T-cell Immune Response
Current Genomics Amygdalar Atrophy in Early Alzheimer’s Disease
Current Alzheimer Research Central Nervous System Disorders Associated to Immune Checkpoint Inhibitors
Current Cancer Therapy Reviews HIV-1, Methamphetamine and Astrocyte Glutamate Regulation: Combined Excitotoxic Implications for Neuro-AIDS
Current HIV Research Mouse Models of Autoimmune Uveitis
Current Pharmaceutical Design Tau-Focused Immunotherapy for Alzheimers Disease and Related Tauopathies
Current Alzheimer Research Immunotherapy for Alzheimers Disease: Rational Basis in Ongoing Clinical Trials
Current Pharmaceutical Design Targeted Blood-to-Brain Drug Delivery – 10 Key Development Criteria
Current Pharmaceutical Biotechnology Mechanisms of Neuronal Injury and Death in HIV-1 Associated Dementia
Current HIV Research From Mice to Macaques – Animal Models of HIV Nervous System Disease
Current HIV Research Subunit Protein Vaccines: Theoretical and Practical Considerations for HIV-1
Current Molecular Medicine Neural Progenitors and HIV-1- Associated Central Nervous System Disease in Adults and Children
Current HIV Research Neurotransmitter Effects in Human Immunodeficiency Virus (HIV) and Simian Immuno-Deficiency Virus (SIV) Infection
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Stem Cells in Stroke Repair: Current Success & Future Prospects
CNS & Neurological Disorders - Drug Targets Gibbs Sampling Shows Possibilities of B-Cell Epitope Signatures
Protein & Peptide Letters Zolpidem Arousing Effect in Persistent Vegetative State Patients: Autonomic, EEG and Behavioral Assessment
Current Pharmaceutical Design Biochemical Markers of Autoimmune Diseases of the Nervous System
Current Pharmaceutical Design Inhibitors of Cholinesterases in Pharmacology: the Current Trends
Mini-Reviews in Medicinal Chemistry