Generic placeholder image

Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Flexible Crosslinked Benzhydry Support for Gel-Phase Peptide Synthesis

Author(s): I.M. Krishna Kumar and Beena Mathew

Volume 9, Issue 2, 2002

Page: [167 - 172] Pages: 6

DOI: 10.2174/0929866023408913

Price: $65


An amphiphilic support was developed by the suspension polymerization of styrene and 1,4-butanediol dimethacrylate. The copolymer was converted to benzhydryl resin, BDDMA-PS-BH, by a two-step polymer analogous reaction. This resin was employed as a support for the synthesis of delta sleep inducing peptide (DSIP), Trp-Ala-Gly-Gly-Asp-Ala-Ser- Gly-Glu, in high yield and purity by Fmoc / t-Bu tactics.

Keywords: gel, phase peptide, delta sleep inducing peptide, solid-phase peptide

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy