Atomic Force Microscopy and Proteins

Luciano   Paulino   de Silva

doi:10.2174/0929866023408869

Abstract

This review briefly introduces the principles of atomic force microscopy (AFM) applied to protein samples. AFM provides three-dimensional surface images of the proteins with high resolution. The advantage of AFM for protein studies is that AFM can visualize directly the molecule under physiological conditions without previous treatment. AFM operated in the force-spectroscopy mode is now a widespread technique, often used to investigate ligand-receptor interactions with the goal of measuring forces at the individual molecule level.

Keywords: afm, force spectroscopy, proteins adsorption, proteins structure, probe, sample interaction, afm imaging

« Previous Next »

Rights & Permissions Print Cite

Protein & Peptide Letters

Title: Atomic Force Microscopy and Proteins

Volume: 9 Issue: 2

Author(s): Luciano Paulino de Silva

Affiliation:

Keywords: afm, force spectroscopy, proteins adsorption, proteins structure, probe, sample interaction, afm imaging

Abstract: This review briefly introduces the principles of atomic force microscopy (AFM) applied to protein samples. AFM provides three-dimensional surface images of the proteins with high resolution. The advantage of AFM for protein studies is that AFM can visualize directly the molecule under physiological conditions without previous treatment. AFM operated in the force-spectroscopy mode is now a widespread technique, often used to investigate ligand-receptor interactions with the goal of measuring forces at the individual molecule level.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

de Silva Paulino Luciano, Atomic Force Microscopy and Proteins, Protein & Peptide Letters 2002; 9 (2) . https://dx.doi.org/10.2174/0929866023408869

DOI https://dx.doi.org/10.2174/0929866023408869	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305

About this journal

Call for Papers in Thematic Issues

Submission closes on : 01 February, 2025

Therapeutic Proteins and Peptides of Plant Origin

Plants are still the major repository of biologically active substances. In the last two decades, however, natural peptides and proteins of plant origin have gained increasing attention due to their pharmacological activities over a variety of human illnesses, including those mediated by infections and parasitosis and those involving different cellular ...read more

Guest Editor(s): Dr. Márcio Viana Ramos