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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

The Prevention of Preterm Labour - Corticotropin Releasing Hormone Type 1 Receptors as a Target for Drug Design and Development

Author(s): P. A. Keller, K. Kirkwood, J. Morgan, S. Westcott and A. McCluskey

Volume 3, Issue 4, 2003

Page: [295 - 303] Pages: 9

DOI: 10.2174/1389557033488105

Price: $65


The role of the corticotropin releasing hormone in the onset of labour and the subsequent medicinal chemistry implications of CRH antagonists for the prevention of premature birth, and identification of the CRH type 1 receptor as the target for this drug design, are reviewed here.

Keywords: Corticotropin Releasing Hormone (CRH),, premature birth, antagonists

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