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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Antimicrobial Peptides from Anurans Skin Secretions

Author(s): Anna Christina C. Nascimento, Wagner Fontes, Antonio Sebben and Mariana S. Castro

Volume 10, Issue 3, 2003

Page: [227 - 238] Pages: 12

DOI: 10.2174/0929866033478933

Price: $65


This article is an overview of antimicrobial peptides found in anurans skin secretions. These molecules constitute an initial barrier against microbial infections because of their activity against a large array of microorganisms. These peptides hold remarkable pharmaceutical and technological interest since they selectively kill microorganisms and are unlikely to induce resistance in pathogens. Also, outstanding synergism occurs when these peptides are combined with classic antibiotics and other antimicrobial peptides.

Keywords: amphibians, skin secretion, antimicrobial peptides, amphipathic -helix

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