Abstract
This article is an overview of antimicrobial peptides found in anurans skin secretions. These molecules constitute an initial barrier against microbial infections because of their activity against a large array of microorganisms. These peptides hold remarkable pharmaceutical and technological interest since they selectively kill microorganisms and are unlikely to induce resistance in pathogens. Also, outstanding synergism occurs when these peptides are combined with classic antibiotics and other antimicrobial peptides.
Keywords: amphibians, skin secretion, antimicrobial peptides, amphipathic -helix
Protein & Peptide Letters
Title: Antimicrobial Peptides from Anurans Skin Secretions
Volume: 10 Issue: 3
Author(s): Anna Christina C. Nascimento, Wagner Fontes, Antonio Sebben and Mariana S. Castro
Affiliation:
Keywords: amphibians, skin secretion, antimicrobial peptides, amphipathic -helix
Abstract: This article is an overview of antimicrobial peptides found in anurans skin secretions. These molecules constitute an initial barrier against microbial infections because of their activity against a large array of microorganisms. These peptides hold remarkable pharmaceutical and technological interest since they selectively kill microorganisms and are unlikely to induce resistance in pathogens. Also, outstanding synergism occurs when these peptides are combined with classic antibiotics and other antimicrobial peptides.
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Cite this article as:
Nascimento C. Anna Christina, Fontes Wagner, Sebben Antonio and Castro S. Mariana, Antimicrobial Peptides from Anurans Skin Secretions, Protein & Peptide Letters 2003; 10 (3) . https://dx.doi.org/10.2174/0929866033478933
DOI https://dx.doi.org/10.2174/0929866033478933 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
Call for Papers in Thematic Issues
Therapeutic Proteins and Peptides of Plant Origin
Plants are still the major repository of biologically active substances. In the last two decades, however, natural peptides and proteins of plant origin have gained increasing attention due to their pharmacological activities over a variety of human illnesses, including those mediated by infections and parasitosis and those involving different cellular ...read more
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