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Current Analytical Chemistry

Editor-in-Chief

ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review

Author(s): Colin S. Creaser and Lucy Ratcliffe

Volume 2, Issue 1, 2006

Page: [9 - 15] Pages: 7

DOI: 10.2174/157341106775197420

Price: $65

Abstract

Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of APMALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.

Keywords: Atmospheric pressure, MALDI, Mass spectrometry


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