Abstract
Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of APMALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.
Keywords: Atmospheric pressure, MALDI, Mass spectrometry
Current Analytical Chemistry
Title: Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review
Volume: 2 Issue: 1
Author(s): Colin S. Creaser and Lucy Ratcliffe
Affiliation:
Keywords: Atmospheric pressure, MALDI, Mass spectrometry
Abstract: Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of APMALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.
Export Options
About this article
Cite this article as:
Creaser S. Colin and Ratcliffe Lucy, Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review, Current Analytical Chemistry 2006; 2 (1) . https://dx.doi.org/10.2174/157341106775197420
DOI https://dx.doi.org/10.2174/157341106775197420 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
Call for Papers in Thematic Issues
Advancements in biomedicine, corrosion inhibition/monitoring, and lubrication of carbon dots
Carbon dots, a class of carbon-based nanomaterials, have garnered substantial interest in various scientific and engineering fields due to their unique properties, including excellent optical properties, outstanding biocompatibility, easy preparation, good dispersity, ultrasmall size, low toxicity and environmental friendliness. This special issue of Current Analytical Chemistry aims to showcase cutting-edge ...read more
Applications of artificial intelligence in chemical analysis
Artificial intelligence (AI) has demonstrated its versatility in almost all scientific fields, especially analytical chemistry, which is leading the way in the integration of AI. According to Chemical Abstract Services, one of the major disciplines contributing to AI-related publications and patents is analytical chemistry. That?s because techniques such as deep ...read more
Bioanalytical and Biosensor Technologies for Target Molecules
Bioanalytical and biosensor technologies constitute the core of detecting and sensing diverse molecules within living organisms, encompassing proteins, DNA, small molecular metabolites, and beyond. These molecules assume pivotal roles in biological processes, rendering their analysis and sensing indispensable for comprehending biological phenomena and unraveling disease mechanisms. In the current landscape ...read more
Biogeochemistry: global environmental research and management
his issue focuses on the bio-pathways of trace elements (Ni, Co, Cr, Mn, Cd, Pb, Zn and REE) in soil, plant and atmospheric systems. Specific interest in the application of phytotechnologies that utilise hyperaccumulator plants (agro/phytomining). On the basis of understanding the migration and transformation of trace elements in ecosystem, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Future of Diabetes Management by Healthy Probiotic Microorganisms
Current Diabetes Reviews Metabolic Features of Alcoholic Liver Disease
Reviews on Recent Clinical Trials A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements
Recent Patents on Food, Nutrition & Agriculture Combination Therapy with Hepatocyte Growth Factor and Oseltamivir Confers Enhanced Protection Against Influenza Viral Pneumonia
Current Molecular Medicine Nutri-epigenomic Studies Related to Neural Tube Defects: Does Folate Affect Neural Tube Closure Via Changes in DNA Methylation?
Mini-Reviews in Medicinal Chemistry Insulin-like Growth Factor-1 Receptor (IGF-1R) Kinase Inhibitors in Cancer Therapy: Advances and Perspectives
Current Pharmaceutical Design Systematic Understanding of the Mechanisms of <i>Flos Chrysanthemi Indici</i>-mediated Effects on Hypertension <i>via</i> Computational Target Fishing
Combinatorial Chemistry & High Throughput Screening Gold Nanoparticles; Potential Nanotheranostic Agent in Breast Cancer: A Comprehensive Review with Systematic Search Strategy
Current Drug Metabolism Study of Hypolipidemic and Antioxidant Activities of Anvillea radiata Coss & Durieu in Diabetic Rats
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Brachytherapy: State of the Art and Possible Improvements
Anti-Cancer Agents in Medicinal Chemistry Role of Growth Factors in the Pathogenesis of Tissue Fibrosis in Systemic Sclerosis
Current Rheumatology Reviews Drug Acyl Glucuronides: Reactivity and Analytical Implication
Current Pharmaceutical Analysis Stem Cell-Based Therapies and Immunomodulatory Approaches in Newly Diagnosed Type 1 Diabetes
Current Stem Cell Research & Therapy Isoflavones and Bone Health
Current Women`s Health Reviews Olfactory Loss and Dysfunction in Ciliopathies: Molecular Mechanisms and Potential Therapies
Current Medicinal Chemistry Enhanced Transdermal Delivery of Epidermal Growth Factor Facilitated by Dual Peptide Chaperone Motifs
Protein & Peptide Letters From Laptop to Benchtop to Bedside: Structure-based Drug Design on Protein Targets
Current Pharmaceutical Design Immunotherapy with Dendritic Cells as a Cancer Treatment: Perspectives and Therapeutic Potential
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery [General Articles] Intracellular Thiol Concentration Modulating Inflammatory Response: Influence on the Regulation of Cell Functions Through Cysteine Prodrug Approach
Current Medicinal Chemistry Interplay of Breast Cancer Resistance Protein (BCRP) and Metabolizing Enzymes
Current Drug Metabolism