Platelet ADP Receptors and their Antagonists

Patricia      Benoit; Jean-Michel      Dogné

Abstract

ADP plays a crucial role in haemostasis and thrombosis and its receptors are potential target for antithrombotic drugs.The knowledge of the ADP-receptors has been amplified by recent discoveries. This review highlights the ADP-receptors models and their antagonists described in the recent literature, mainly the thienopyridine derivatives.

Keywords: adenosine diphosphate, adp receptors, receptors, antithrombotics, platelets

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