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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Monoamine Oxidases: to Inhibit or Not to Inhibit

Author(s): R. R. Ramsay and M. B. Gravestock

Volume 3, Issue 2, 2003

Page: [129 - 136] Pages: 8

DOI: 10.2174/1389557033405287

Price: $65


Monoamine oxidase (MAO) inhibitors were developed as antidepressants but many drugs, including the novel oxazolidinone antibacterial agents, share similar molecular properties and have MAO inhibitory activity. Factors important for binding antidepressants and modifications to decrease binding of oxazolidinones to avoid undesirable vascular effects are discussed.

Keywords: monoamine oxidase, mao, mao inhibitor, monoamine oxidase inhibitor, antidepressants, oxazolidinones

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