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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Content of the Hmg-17 Chromosomal Protein in Porcine Tissues

Author(s): Vassiliki A. Boumba, Konstantin Seferiadis and Theodore Vougiouklakis

Volume 11, Issue 6, 2004

Page: [515 - 519] Pages: 5

DOI: 10.2174/0929866043406193

Price: $65


HMG-17 proteins are nucleosomal proteins, implicated in control of chromatin structure and transcription, in a way that has not yet been fully understood. In this report, quantification of HMG-17 in porcine tissues was performed, by ELISA, using previously produced and characterized specific rabbit anti- HMG-17 antibodies. Our results showed high levels of HMG-17 compared to the DNA and H1 content of the tissues (on the contrary to previous reports), and more specifically that there were 1.7 molecules of HMG-17 per molecule of histone H1.

Keywords: hmg-17, histone h1, quantification, elisa, tissue distribution.

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