Abstract
Cross-linking and cross-bridging are highly versatile methods of creating composite protein structures with desired mechanical properties such as deformation endurance, elasticity, extensibility, and stability under intensive and repetitive sheering forces. Cross-linking and crossbridging are distinguished by the bonds that hold the structural components together. Cross-linking implies a covalent association, whereas cross-bridging depends on biological recognition, in which hydrogen bonding, ionic, and hydrophobic interactions predominate. Cross-bridged structures are found in all living systems. Cytoskeletal interaction, cell invasion by pathogens, fertilization, and cellulosomal degradation of cellulose are all examples of biological processes in which cross-bridging proteins play a key role. This article will review the different types of biological cross-bridging proteins that are known and discuss their emerging nano- and biotechnological applications.
Keywords: Cross bridging, biotechnology, nanotechnology, self-assembly, scaffold
Current Protein & Peptide Science
Title: Cross Bridging Proteins in Nature and their Utilization in Bio- and Nanotechnology
Volume: 5 Issue: 1
Author(s): Ilan Levy and Oded Shoseyov
Affiliation:
Keywords: Cross bridging, biotechnology, nanotechnology, self-assembly, scaffold
Abstract: Cross-linking and cross-bridging are highly versatile methods of creating composite protein structures with desired mechanical properties such as deformation endurance, elasticity, extensibility, and stability under intensive and repetitive sheering forces. Cross-linking and crossbridging are distinguished by the bonds that hold the structural components together. Cross-linking implies a covalent association, whereas cross-bridging depends on biological recognition, in which hydrogen bonding, ionic, and hydrophobic interactions predominate. Cross-bridged structures are found in all living systems. Cytoskeletal interaction, cell invasion by pathogens, fertilization, and cellulosomal degradation of cellulose are all examples of biological processes in which cross-bridging proteins play a key role. This article will review the different types of biological cross-bridging proteins that are known and discuss their emerging nano- and biotechnological applications.
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Cite this article as:
Levy Ilan and Shoseyov Oded, Cross Bridging Proteins in Nature and their Utilization in Bio- and Nanotechnology, Current Protein & Peptide Science 2004; 5 (1) . https://dx.doi.org/10.2174/1389203043486919
DOI https://dx.doi.org/10.2174/1389203043486919 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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