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Current HIV Research

Editor-in-Chief

ISSN (Print): 1570-162X
ISSN (Online): 1873-4251

Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection

Author(s): Giuseppe Barbaro

Volume 4 , Issue 1 , 2006

Page: [79 - 85] Pages: 7

DOI: 10.2174/157016206775197664

Price: $65

Abstract

Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.

Keywords: Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease


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