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Current Protein & Peptide Science

Editor-in-Chief

ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

Imaging Proteins with Atomic Force Microscopy: An Overview

Author(s): Luciano P. Silva

Volume 6, Issue 4, 2005

Page: [387 - 395] Pages: 9

DOI: 10.2174/1389203054546389

Price: $65

Abstract

Atomic force microscopy (AFM) has become a common tool for biophysical studies of proteins; mainly due its property to perform characterizations near physiological conditions. The tertiary and quaternary structures, forces driving folding-unfolding processes, and secondary structure elements can be studied in their native environments allowing high resolution level associated with small distortions. This review outlines the operational principles and applications of AFM for protein biophysics.

Keywords: atomic force microscopy, afm, force spectroscopy, protein, protein adsorption

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