Abstract
Atomic force microscopy (AFM) has become a common tool for biophysical studies of proteins; mainly due its property to perform characterizations near physiological conditions. The tertiary and quaternary structures, forces driving folding-unfolding processes, and secondary structure elements can be studied in their native environments allowing high resolution level associated with small distortions. This review outlines the operational principles and applications of AFM for protein biophysics.
Keywords: atomic force microscopy, afm, force spectroscopy, protein, protein adsorption
Current Protein & Peptide Science
Title: Imaging Proteins with Atomic Force Microscopy: An Overview
Volume: 6 Issue: 4
Author(s): Luciano P. Silva
Affiliation:
Keywords: atomic force microscopy, afm, force spectroscopy, protein, protein adsorption
Abstract: Atomic force microscopy (AFM) has become a common tool for biophysical studies of proteins; mainly due its property to perform characterizations near physiological conditions. The tertiary and quaternary structures, forces driving folding-unfolding processes, and secondary structure elements can be studied in their native environments allowing high resolution level associated with small distortions. This review outlines the operational principles and applications of AFM for protein biophysics.
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Cite this article as:
Silva P. Luciano, Imaging Proteins with Atomic Force Microscopy: An Overview, Current Protein & Peptide Science 2005; 6 (4) . https://dx.doi.org/10.2174/1389203054546389
DOI https://dx.doi.org/10.2174/1389203054546389 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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