Abstract
While the post-genomic era could lead into new targets for antimalarial drug development, herein few successful targets including medicinals involved in those processes are presented. Further, contribution of bioinorganic chemistry has also started to make its impact in the field of pharmaceuticals. Therefore, metal chelators, selected organometallics, and metalloantimalarials that would offer potential therapeutic drugs are also discussed. Finally, a brief summary on chloroquine-resistance mechanism(s) has been included.
Keywords: therapeutic drugs, chloroquine, drug-resistance, metalloantimalarials, malaria
Mini-Reviews in Medicinal Chemistry
Title: Therapeutic Drugs for Targeting Chloroquine Resistance in Malaria
Volume: 5 Issue: 4
Author(s): Vijay Sharma
Affiliation:
Keywords: therapeutic drugs, chloroquine, drug-resistance, metalloantimalarials, malaria
Abstract: While the post-genomic era could lead into new targets for antimalarial drug development, herein few successful targets including medicinals involved in those processes are presented. Further, contribution of bioinorganic chemistry has also started to make its impact in the field of pharmaceuticals. Therefore, metal chelators, selected organometallics, and metalloantimalarials that would offer potential therapeutic drugs are also discussed. Finally, a brief summary on chloroquine-resistance mechanism(s) has been included.
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Cite this article as:
Sharma Vijay, Therapeutic Drugs for Targeting Chloroquine Resistance in Malaria, Mini-Reviews in Medicinal Chemistry 2005; 5 (4) . https://dx.doi.org/10.2174/1389557053544029
DOI https://dx.doi.org/10.2174/1389557053544029 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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