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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

The Total Synthesis of Pitipeptolide A

Author(s): Yungui Peng, Heungwing Pang, Zhengshuang Xu and Tao Ye

Volume 2, Issue 8, 2005

Page: [703 - 706] Pages: 4

DOI: 10.2174/157017805774717481

Price: $65


An efficient synthesis of the marine cyanobacterium metabolite pitipeptolide A is presented. The approach incorporates a variety of peptide coupling methods, asymmetric synthesis and macrocyclization. The route is versatile and allows scope for structural modification.

Keywords: Cyanobacteria, Total synthesis, Depsipeptide, Macrocyclization, Lyngbya majuscula

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