Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes

Title: Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes

Volume: 2 Issue: 6

Author(s): M. Molteni and M. Zanda

Affiliation:

Keywords: nitroalkenes, fluorinated building blocks, michael addition, diels-alder, dipolar reactions, (nitroaldol) reaction, tbaf, mukaiyama-like conditions

Abstract: The Michael addition of ketone-derived enamines to γ-fluoro-α-nitroalkenes provides in moderate to good isolated yields the corresponding β-fluoroalkyl γ-nitroketones, which can be reduced to β-fluoroalkyl γ- nitroalcohols.

Cite this article as:

Molteni M. and Zanda M., Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes, Letters in Organic Chemistry 2005; 2 (6) . https://dx.doi.org/10.2174/1570178054640769