Abstract
During the last five years, the scientific community has seen a dramatic increase in the number of synthetic methods or strategies to prepare C-linked glycoconjugates. One reason for this increase is that the biological significance and roles of many O- and N-linked glyconconjugates has become evident. This review will summarize the biological importance of glycoconjugates and outline recent advances in the preparation of C-linked glycoconjugates that have appeared in the literature since the new millennium.
Keywords: Asparagine, double-bond isomerization, Ramberg-Backlund rearrangement, Tebbe/Claisen approach, C-Mannosyltryptophan
Current Topics in Medicinal Chemistry
Title: Recent Advances in the Synthesis of C-linked Glycoconjugates
Volume: 5 Issue: 14
Author(s): Elisabeth v. Moos and Robert N. Ben
Affiliation:
Keywords: Asparagine, double-bond isomerization, Ramberg-Backlund rearrangement, Tebbe/Claisen approach, C-Mannosyltryptophan
Abstract: During the last five years, the scientific community has seen a dramatic increase in the number of synthetic methods or strategies to prepare C-linked glycoconjugates. One reason for this increase is that the biological significance and roles of many O- and N-linked glyconconjugates has become evident. This review will summarize the biological importance of glycoconjugates and outline recent advances in the preparation of C-linked glycoconjugates that have appeared in the literature since the new millennium.
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Cite this article as:
Moos v. Elisabeth and Ben N. Robert, Recent Advances in the Synthesis of C-linked Glycoconjugates, Current Topics in Medicinal Chemistry 2005; 5 (14) . https://dx.doi.org/10.2174/156802605774643024
DOI https://dx.doi.org/10.2174/156802605774643024 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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