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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Immunocontinuum: Perspectives in Antimicrobial Peptide Mechanisms of Action and Resistance

Author(s): Nannette Y. Yount and Michael R. Yeaman

Volume 12, Issue 1, 2005

Page: [49 - 67] Pages: 19

DOI: 10.2174/0929866053405959

Price: $65

Abstract

Antimicrobial peptides are present in organisms spanning virtually every kingdom, and employ sophisticated mechanisms to exert rapid microbicidal action consistent with their key roles in host defense. Offsetting these mechanisms, some microbial pathogens have evolved complex countermeasures to neutralize exposure to and subvert mechanisms of antimicrobial peptides. The following discussion highlights recent advances that offer greater understanding of the mechanisms of action and resistance of antimicrobial peptides.

Keywords: antimicrobial, peptide, resistance, mechanism


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