Abstract
Granuloma, a collection of various inflammatory cells composed of lymphocytes, epithelioid cells, giant cells, mononuclear cells, eosinophils, plasma cells, and fibroblasts is a host response to an antigen(s). Specific patterns of the granulomatous response such as necrosis, caseation, and the presence or absence of microorganisms or foreign bodies aid in securing the diagnosis. The common causes of granulomatous lung disease include sarcoidosis, hypersensitivity pneumonitis, Wegeners granulomatosis, mycobacterial infections, fungal diseases, parasitic infestations, and drugs. This review, designed for practicing pulmonologists, emphasizes diagnosis and treatment of some of the common pulmonary granulomas.
Keywords: T lymphocytes, Sarcoidosis, Bronchoalveolar Lavage, Chronic beryllium disease, Tuberculosis
Current Respiratory Medicine Reviews
Title: Granulomatous Lung Disease. Disease for Pulmomologists: Diagnosis and Treatment
Volume: 3 Issue: 3
Author(s): Hidenobu Shigemitsu and Om P. Sharma
Affiliation:
Keywords: T lymphocytes, Sarcoidosis, Bronchoalveolar Lavage, Chronic beryllium disease, Tuberculosis
Abstract: Granuloma, a collection of various inflammatory cells composed of lymphocytes, epithelioid cells, giant cells, mononuclear cells, eosinophils, plasma cells, and fibroblasts is a host response to an antigen(s). Specific patterns of the granulomatous response such as necrosis, caseation, and the presence or absence of microorganisms or foreign bodies aid in securing the diagnosis. The common causes of granulomatous lung disease include sarcoidosis, hypersensitivity pneumonitis, Wegeners granulomatosis, mycobacterial infections, fungal diseases, parasitic infestations, and drugs. This review, designed for practicing pulmonologists, emphasizes diagnosis and treatment of some of the common pulmonary granulomas.
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Cite this article as:
Hidenobu Shigemitsu and Om P. Sharma , Granulomatous Lung Disease. Disease for Pulmomologists: Diagnosis and Treatment, Current Respiratory Medicine Reviews 2007; 3 (3) . https://dx.doi.org/10.2174/157339807781387535
DOI https://dx.doi.org/10.2174/157339807781387535 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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