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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin

Author(s): Chenglong Wu, Li Cheng, Ying Li, Dong Guo, Shuyan Yu, Xianxue Wu and Yuquan Wei

Volume 4, Issue 5, 2007

Page: [366 - 369] Pages: 4

DOI: 10.2174/157017807781212021

Price: $65

Abstract

A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.

Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt


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