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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Microwave-Promoted Ring Opening Reaction of Azalactones

Author(s): Ricardo H. Valdes, Donato A.G. Aranda, Heiddy M. Alvarez and Octavio A.C. Antunes

Volume 4, Issue 1, 2007

Page: [35 - 38] Pages: 4

DOI: 10.2174/157017807780037360

Price: $65

Abstract

α,β-Dehydroamino amides are important intermediates for the synthesis of biologically active molecules. A rapid procedure is reported for the synthesis of α,β-dehydroamino amides from azalactones under MW radiation. Azalactones were produced via Erlenmeyer reaction and submitted to ring opening reactions under MW during 15-30 min. Over 90% yields were obtained.

Keywords: α,β-Dehydroamino amides, azalactones, ring opening, microwave irradiation


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