Abstract
The expression of Panton-Valentine leukocidin (PVL) has been implicated as a virulence factor for communityacquired Staphylococcus aureus pneumonia with most reported cases involving methicillin-resistant strains. Here we describe a case of community-acquired, PVL-positive methicillin-sensitive Staphylococcus aureus (MSSA) sufficiently virulent to cause rapidly progressive necrotizing pneumonia, massive pulmonary hemorrhage, sepsis, and death in a patient without conventional risk factors (diabetes, advanced age). To our knowledge, this is the first case report of a fatal necrotizing pneumonia caused by PVL-positive MSSA in Los Angeles County.
Keywords: PVL, MSSA, community-acquired necrotizing pneumonia and massive hemoptysis
Current Respiratory Medicine Reviews
Title: A Case of Fatal Community-Acquired Necrotizing Pneumonia Caused by Panton-Valentine Leukocidin Positive Methicillin-Sensitive Staphylococcus Aureus
Volume: 3 Issue: 1
Author(s): Narimon Honarpour and Jenny T. Mao
Affiliation:
Keywords: PVL, MSSA, community-acquired necrotizing pneumonia and massive hemoptysis
Abstract: The expression of Panton-Valentine leukocidin (PVL) has been implicated as a virulence factor for communityacquired Staphylococcus aureus pneumonia with most reported cases involving methicillin-resistant strains. Here we describe a case of community-acquired, PVL-positive methicillin-sensitive Staphylococcus aureus (MSSA) sufficiently virulent to cause rapidly progressive necrotizing pneumonia, massive pulmonary hemorrhage, sepsis, and death in a patient without conventional risk factors (diabetes, advanced age). To our knowledge, this is the first case report of a fatal necrotizing pneumonia caused by PVL-positive MSSA in Los Angeles County.
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Cite this article as:
Honarpour Narimon and Mao T. Jenny, A Case of Fatal Community-Acquired Necrotizing Pneumonia Caused by Panton-Valentine Leukocidin Positive Methicillin-Sensitive Staphylococcus Aureus, Current Respiratory Medicine Reviews 2007; 3 (1) . https://dx.doi.org/10.2174/157339807779941776
DOI https://dx.doi.org/10.2174/157339807779941776 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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