A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O

Title: A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O

Volume: 3 Issue: 12

Author(s): Javad Azizian, Ali Saffar-Teluri and Ali Asadi

Affiliation:

Keywords: Ultrasonic, 1,3-dipolar cycloaddition, spiro pyrolidines, azomethine ylides, stereoselective, endo-transition state

Abstract: Ultrasonic irradiation effectively promotes the 1,3-dipolar cycloaddition reaction of azomethine ylides generated from L-phenyl alanine and isatin derivatives via the decarboxylative with N-aryl maleimides in aqueous solution under stereoselective cycloaddition via endo-transition state to give new spiro pyrrolidine cycloadducts.

Cite this article as:

Azizian Javad, Saffar-Teluri Ali and Asadi Ali, A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O, Letters in Organic Chemistry 2006; 3 (12) . https://dx.doi.org/10.2174/157017806779468068