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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Lessons from Leptins Molecular Biology: Potential Therapeutic Actions of Recombinant Leptin and Leptin-Related Compounds

Author(s): M. L. G. Correia and W. G. Haynes

Volume 7 , Issue 1 , 2007

Page: [31 - 38] Pages: 8

DOI: 10.2174/138955707779317858

Price: $65

Abstract

Leptin, a peptide secreted by the white adipose tissue, circulates to the central nervous system and signals the status of body energy stores, regulating feeding behavior and energy balance. As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment.

Keywords: Obesity, obesity treatment, leptin, leptin resistance, lipodystrophy


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