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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Preservation Solutions for Solid Organ Transplantation

Author(s): C. H. Wilson, N. R. Brook and D. Talbot

Volume 6, Issue 10, 2006

Page: [1081 - 1090] Pages: 10

DOI: 10.2174/138955706778560148

Price: $65

Abstract

Solid organ transplantation was one of the greatest medical advances of the 20th century. Current preservation technology falls short of maintaining organs ex vivo in perpetuity. This review examines the biochemical basis of organ degradation in response to ischaemia, preservation solution composition and potential future organ preservation technology.

Keywords: Organ transplantation, preservation solutions, machine perfusion preservation, hypothermia


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