Abstract
In order to identify proteins that bind to the PDZ domain of Erbin, we tested the C-termini of several proteins in a yeast two-hybrid assay. ErbB2, APC, β-catenin, c-Rel and HTLV-1 Tax were identified as ligands of the PDZ domain of Erbin. The interactions were verified by co-immunoprecipitation experiments. These findings demonstrate the promiscuity of the PDZ domain of Erbin.
Keywords: Erbin, PDZ domain, ErbB2, APC, c-Rel, HTLV-1 Tax
Protein & Peptide Letters
Title: Interaction Partners of the PDZ Domain of Erbin
Volume: 13 Issue: 9
Author(s): Angelika Ress and Karin Moelling
Affiliation:
Keywords: Erbin, PDZ domain, ErbB2, APC, c-Rel, HTLV-1 Tax
Abstract: In order to identify proteins that bind to the PDZ domain of Erbin, we tested the C-termini of several proteins in a yeast two-hybrid assay. ErbB2, APC, β-catenin, c-Rel and HTLV-1 Tax were identified as ligands of the PDZ domain of Erbin. The interactions were verified by co-immunoprecipitation experiments. These findings demonstrate the promiscuity of the PDZ domain of Erbin.
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Cite this article as:
Ress Angelika and Moelling Karin, Interaction Partners of the PDZ Domain of Erbin, Protein & Peptide Letters 2006; 13 (9) . https://dx.doi.org/10.2174/092986606778256126
DOI https://dx.doi.org/10.2174/092986606778256126 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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