Abstract
A highly efficient stereoselective total synthesis of piperidine alkaloid (+)-sedamine has been described utilizing two regioselective ring opening reactions of epoxide with vinyl metallic reagent and a ring closing metathesis reaction as the key steps.
Keywords: (+)-sedamine, vinylmetallic reagent, ADH, regioselective epoxide opening, RCM
Letters in Organic Chemistry
Title: Stereoselective Total Synthesis of (+)-Sedamine
Volume: 3 Issue: 2
Author(s): Jagat C. Borah, Joshodeep Boruwa and Nabin C. Barua
Affiliation:
Keywords: (+)-sedamine, vinylmetallic reagent, ADH, regioselective epoxide opening, RCM
Abstract: A highly efficient stereoselective total synthesis of piperidine alkaloid (+)-sedamine has been described utilizing two regioselective ring opening reactions of epoxide with vinyl metallic reagent and a ring closing metathesis reaction as the key steps.
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Cite this article as:
Borah C. Jagat, Boruwa Joshodeep and Barua C. Nabin, Stereoselective Total Synthesis of (+)-Sedamine, Letters in Organic Chemistry 2006; 3 (2) . https://dx.doi.org/10.2174/157017806775224297
DOI https://dx.doi.org/10.2174/157017806775224297 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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