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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis (Experimental Section)

Author(s): Fazal Naeem, Nida Ambreen, Khalid M. Khan, Yuan-Ping Pang, Bernadette Cusack, Elliot Richelson, Awais Anwar, Wolfgang Voelter and Javid H. Zaidi

Volume 3, Issue 1, 2006

Page: [21 - 24] Pages: 4

DOI: 10.2174/157017806774964530

Price: $65


The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

Keywords: Neurotensin, partial peptidic mimic, drug design, synthesis

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