Src Inhibitors as Potential Therapeutic Agents for Human Cancers

Title: Src Inhibitors as Potential Therapeutic Agents for Human Cancers

Volume: 6 Issue: 6

Author(s): Jose G. Trevino, Justin M. Summy and Gary E. Gallick

Affiliation:

Keywords: Src family kinase, Inhibitors, Adenocarcinoma

Abstract: Selective inhibitors of the Src family of protein tyrosine kinases have been developed as therapeutic agents for human tumors, some of which are now in various stages of clinical trial. In this review, recently described novel small molecule ATP-competitive Src inhibitors are discussed, with an emphasis on their potential use as therapeutic inhibitors for advanced-stage malignancies.

Cite this article as:

Trevino G. Jose, Summy M. Justin and Gallick E. Gary, Src Inhibitors as Potential Therapeutic Agents for Human Cancers, Mini-Reviews in Medicinal Chemistry 2006; 6(6) . https://dx.doi.org/10.2174/138955706777435724