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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Development of Radiolabeled Compounds for Myocardial Perfusion Imaging

Author(s): Xiao Lin, Junbo Zhang, Xuebin Wang, Zhigang Tang, Xianzhong Zhang and Jie Lu

Volume 18, Issue 8, 2012

Page: [1041 - 1057] Pages: 17

DOI: 10.2174/138161212799315876

Price: $65


Coronary artery disease (CAD) is the main cause of death and remains a major health problem worldwide. Myocardial perfu-sion imaging is a well established noninvasive method for assessing CAD. This review summarizes the development of various ra-diotracers for myocardial perfusion imaging, including single photon emission computed tomography (SPECT) perfusion imaging agents and positron emission tomography (PET) perfusion imaging agents and introduces novel basic research data related to this area. In addi-tion, the current state of the art in myocardial perfusion imaging agents and the future direction are discussed in this review.

Keywords: Radiotracers, myocardial, perfusion, imaging, nuclear medicine, Coronary artery disease (CAD), single photon emission computed tomography (SPECT), positron emission tomography (PET), infarction

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