Abstract
Pheophorbide a is a clorophyll catabolite that recently has drawn the attention of several investigators for its potential in photodynamic therapy. In this review we summarize its photophysical properties, phototoxicity, cellular localization, biodistribution and PDT activity as a free or conjugated molecule.
Keywords: Photodynamic therapy, Pheophorbide a, Photophysical parameters, Tissue distribution, Imaging, In vivo activity, clorophyll, phototoxicity, PDT activity, photochemical reaction
Current Medicinal Chemistry
Title: The Chlorophyll Catabolite Pheophorbide a as a Photosensitizer for the Photodynamic Therapy
Volume: 19 Issue: 6
Author(s): L. E. Xodo, V. Rapozzi, M. Zacchigna, S. Drioli and S. Zorzet
Affiliation:
Keywords: Photodynamic therapy, Pheophorbide a, Photophysical parameters, Tissue distribution, Imaging, In vivo activity, clorophyll, phototoxicity, PDT activity, photochemical reaction
Abstract: Pheophorbide a is a clorophyll catabolite that recently has drawn the attention of several investigators for its potential in photodynamic therapy. In this review we summarize its photophysical properties, phototoxicity, cellular localization, biodistribution and PDT activity as a free or conjugated molecule.
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Cite this article as:
E. Xodo L., Rapozzi V., Zacchigna M., Drioli S. and Zorzet S., The Chlorophyll Catabolite Pheophorbide a as a Photosensitizer for the Photodynamic Therapy, Current Medicinal Chemistry 2012; 19 (6) . https://dx.doi.org/10.2174/092986712799034879
DOI https://dx.doi.org/10.2174/092986712799034879 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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