Abstract
Neutrophils constitute the first line of host defense against pathogens. In the present study 2-D gel electrophoresis- mass spectrometry technology was employed to analyze the human resting neutrophils proteome. One hundred and two conserved spots were subjected to peptide mass fingerprinting, yielding 22 identifications. Among the identified proteins, nine are related to the inflammatory process, two polypeptides are assigned to metabolic functions and five are classified as structural.
Keywords: Neutrophils, proteome, peptide mass fingerprinting, inflammatory response
Protein & Peptide Letters
Title: Proteome Analysis of Resting Human Neutrophils
Volume: 13 Issue: 5
Author(s): Mariana d. S. Castro, Natan M. de Sa, Renata P. Gadelha, Marcelo V. de Sousa, Carlos A. O. Ricart, Belchor Fontes and Wagner Fontes
Affiliation:
Keywords: Neutrophils, proteome, peptide mass fingerprinting, inflammatory response
Abstract: Neutrophils constitute the first line of host defense against pathogens. In the present study 2-D gel electrophoresis- mass spectrometry technology was employed to analyze the human resting neutrophils proteome. One hundred and two conserved spots were subjected to peptide mass fingerprinting, yielding 22 identifications. Among the identified proteins, nine are related to the inflammatory process, two polypeptides are assigned to metabolic functions and five are classified as structural.
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Cite this article as:
Castro d. S. Mariana, de Sa M. Natan, Gadelha P. Renata, de Sousa V. Marcelo, Ricart A. O. Carlos, Fontes Belchor and Fontes Wagner, Proteome Analysis of Resting Human Neutrophils, Protein & Peptide Letters 2006; 13 (5) . https://dx.doi.org/10.2174/092986606776819529
DOI https://dx.doi.org/10.2174/092986606776819529 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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