Abstract
The chemistry of chromones is very well known. This system is widely used in organic chemistry as an intermediate compound for the synthesis of numerous hetrocycles. On the other hand, chromones were extensively studied as bioactive compounds. They possess remarkable biological activities, such as antimicrobial, antiviral, anticancer, anti-inflammatory, antioxidant, etc.
This comprehensive review describes the current status and knowledge of natural occurrence, and biological activities of chromones. Recent advances made over the last decade i.e. January 1999 to December 2009 are critically discussed and we have covered about 176 references and more than 350 compounds reported during this period.
Keywords: Chromones, benzopyran-4-ones, occurrence, mast cell stabilizers, biological activity, synthesis of numerous, hetrocycles, antimicrobial, anti-inflammatory, antioxidant
Current Medicinal Chemistry
Title: An Update on Natural Occurrence and Biological Activity of Chromones
Volume: 18 Issue: 25
Author(s): S. K. Sharma, S. Kumar, K. Chand, A. Kathuria, A. Gupta and R. Jain
Affiliation:
Keywords: Chromones, benzopyran-4-ones, occurrence, mast cell stabilizers, biological activity, synthesis of numerous, hetrocycles, antimicrobial, anti-inflammatory, antioxidant
Abstract: The chemistry of chromones is very well known. This system is widely used in organic chemistry as an intermediate compound for the synthesis of numerous hetrocycles. On the other hand, chromones were extensively studied as bioactive compounds. They possess remarkable biological activities, such as antimicrobial, antiviral, anticancer, anti-inflammatory, antioxidant, etc.
This comprehensive review describes the current status and knowledge of natural occurrence, and biological activities of chromones. Recent advances made over the last decade i.e. January 1999 to December 2009 are critically discussed and we have covered about 176 references and more than 350 compounds reported during this period.
Export Options
About this article
Cite this article as:
K. Sharma S., Kumar S., Chand K., Kathuria A., Gupta A. and Jain R., An Update on Natural Occurrence and Biological Activity of Chromones, Current Medicinal Chemistry 2011; 18(25) . https://dx.doi.org/10.2174/092986711803414359
DOI https://dx.doi.org/10.2174/092986711803414359 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |

- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Matrix Metalloproteinases: New Routes to the Use of MT1-MMP As A Therapeutic Target in Angiogenesis-Related Disease
Current Pharmaceutical Design Self-Assembling Peptides: Potential Role in Tumor Targeting
Current Pharmaceutical Biotechnology Integrin Antagonists: A Special Emphasis on Structural Requirements of N-benzoyl-L-biphenylalanines as α4β7 and α4β1 Antagonists
Current Signal Transduction Therapy The Roles of Chromatin Remodeling Proteins in Cancer
Current Protein & Peptide Science The proNGF-p75NTR-Sortilin Signalling Complex as New Target for the Therapeutic Treatment of Parkinsons Disease
CNS & Neurological Disorders - Drug Targets Anti-HER2 Cancer Therapy and Cardiotoxicity
Current Pharmaceutical Design Emerging Biologics in the Treatment of Inflammatory Bowel Disease: What is Around the Corner?
Current Drug Targets Immunomodulating and Anti-Allergic Effects of Negroamaro and Koshu Vitis vinifera Fermented Grape Marc (FGM)
Current Pharmaceutical Design n-3 Polyunsaturated Fatty Acids and the Prevention of Colorectal Cancer: Molecular Mechanisms Involved
Current Medicinal Chemistry Immunology Behind Tumors: A Mini Review
Current Cancer Therapy Reviews Anti-VEGF/VEGFR2 Monoclonal Antibodies and their Combinations with PD-1/PD-L1 Inhibitors in Clinic
Current Cancer Drug Targets Targeting Cytokines, Chemokines and Adhesion Molecules in Rheumatoid Arthritis
Current Rheumatology Reviews CD147 Promotes Melanoma Progression Through Hypoxia-Induced MMP2 Activation
Current Molecular Medicine Therapeutic Uses of HSP90 Inhibitors in Non-Small Cell Lung Carcinoma (NSCLC)
Current Drug Metabolism Allosteric Modulation of Protease-Activated Receptor Signaling
Mini-Reviews in Medicinal Chemistry Advanced Systems for Controlled Drug Delivery from Chemically Modified Elastin-like Recombinamers
Current Organic Chemistry EDITORIAL (Hot Topic: “Signal Transduction and Response to Anti-Cancer Therapy”)
Current Signal Transduction Therapy Nitric Oxide in Cancer Therapeutics: Interaction with Cytotoxic Chemotherapy
Current Pharmaceutical Design Identification of Multiple Subcellular Locations for Proteins in Budding Yeast
Current Bioinformatics A Novel Assay Platform for the Detection of Translation Modulators of Spermidine/ Spermine Acetyltransferase
Current Pharmaceutical Design