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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Highly Facile Regioselective Ring Opening of Epoxides to Halohydrins in the Presence of polyHIPEs (CTAB) and β-cyclodextrins (TSAX) in Water

Author(s): Shengmiao Zhang, Jianding Chen and V. Tamara Perchyonok

Volume 15, Issue 15, 2011

Page: [2690 - 2693] Pages: 4

DOI: 10.2174/138527211796367264

Price: $65

Abstract

Reactions of epoxides with tetrasubstitute ammonium halides in the presence of β-cyclodextrins or polyHIPE in aqueous media afforded vicinal halohydrins in excellent yields via regioselective ring opening of the unsymmetric epoxides.

Keywords: Epoxides, polyHIPEs, beta cyclodextrins, water, regio-selective, Cyclodextrins (CDs), cyclohexene epoxides, epichlorohydrin, aryloxy- methylene epoxide, polyHIPE, halohydrins, chlorosilanes, haloborane, low regiospecificity,, oxiranes


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