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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Towards the Targeted Therapy of Melanoma

Author(s): K. S.M. Smalley and M. Herlyn

Volume 6, Issue 4, 2006

Page: [387 - 393] Pages: 7

DOI: 10.2174/138955706776361402

Price: $65


Novel anti-cancer treatments use knowledge about the underlying biology of the tumor to find suitable molecular targets. The recent years have seen great advances in understanding the biology of melanoma. In the current review we discuss the most promising molecular targets for melanoma and suggest possible strategies for overcoming resistance.

Keywords: Melanoma, melanocyte, BRAF, PI3K, therapy, cancer, proteasome

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