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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Anti-hyperglycemic Potential of Natural Products

Author(s): T. Matsui, I. A. Ogunwande, K. J.M. Abesundara and K. Matsumoto

Volume 6, Issue 3, 2006

Page: [349 - 356] Pages: 8

DOI: 10.2174/138955706776073484

Price: $65

Abstract

In order to evaluate the anti-hyperglycemic effect of natural compounds via the inhibition of α- glucosidase (AGH), the potential inhibitory effect of anthocyanins, caffeic acid analogs, and caffeoylquinic acid analogs have been reviewed. A new AGH assay system to mimic the membrane-bound AGH at the small intestine was proposed and evaluated.

Keywords: Diabetes, α-glucosidase, maltase inhibition, anti-hyperglycemic effect


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