Chemistry and Biological Activities of Buxus Alkaloids

Title: Chemistry and Biological Activities of Buxus Alkaloids

Volume: 7 Issue: 1

Author(s): Yu-Xin Yan, Yun Sun, Zhong-Rong Li, Lin Zhou and Ming-Hua Qiu

Affiliation:

Keywords: Buxaceae, Buxus alkaloid, cyclovirobuxine D, structure modification, biological activity, triterpenoid alkaloids, plant sources, antibacterial, herbal medicine, anti-myocardial ischemia

Abstract: Triterpenoid alkaloids are one of the most important classes that have been studied. Buxus alkaloids are such a type of triterpenoid alkaloids of cycloartenol skeleton with a degraded C-20 side chain, and with the nitrogen containing substituents at C-3 and/or C-20. 219 Buxus alkaloids have been reported so far. This review article focuses on the structural characters, plant sources and biological activities of Buxus alkaloids. This review includes anti-myocardial ischemia, inhibition of acetyl- and butyryl-cholinesterases, cytotoxicity and antibacterial activities. The biological activities, mechanisms and structure modifications of cyclovirobuxine D (CVB-D) are also described.

Cite this article as:

Yan Yu-Xin, Sun Yun, Li Zhong-Rong, Zhou Lin and Qiu Ming-Hua, Chemistry and Biological Activities of Buxus Alkaloids, Current Bioactive Compounds 2011; 7 (1) . https://dx.doi.org/10.2174/157340711795163811