Abstract
Cardiovascular disease is the main cause of death in the United States. Although it is recognized that moderate intensity long-term exercise can decrease the chances of dying from cardiovascular disease by favorably modifying risk factors such as hypertension, obesity, hyperlipidemia, and insulin resistance, physical activity also enhances longevity by mechanisms independent of these risk factors. This review briefly summarizes what is known about the inflammatory nature of atherosclerosis and how long-term aerobic exercise can reduce the atherogenic activity of endothelial cells, blood mononuclear cells, and adipose tissue.
Keywords: Exercise, cardiovascular disease, cardiorespiratory fitness, atherogenesis, vascular endothelial cells, peripheral blood mononuclear cells, adipose tissue, inflammation, cell-mediated immunity, hypertension, obesity, hyperlipidemia, insulin resistance, immunopathogenesis, vascular endothelial cells (VEC), Chlamydia pneumoniae, cytomegalovirus, heat shock protein 60 (Hsp 60), chemokines, prostacyclin PGI2, adrenomedullin, granulopoiesis, immunogens, metalloproteinases, phosphorylation, eNOS protein, adipocytes, lymphocytes, fibroblasts, adipokines, monocytes
Cardiovascular & Hematological Disorders-Drug Targets
Title: Exercise and Cardiovascular Disease
Volume: 10 Issue: 4
Author(s): J. Kelly Smith
Affiliation:
Keywords: Exercise, cardiovascular disease, cardiorespiratory fitness, atherogenesis, vascular endothelial cells, peripheral blood mononuclear cells, adipose tissue, inflammation, cell-mediated immunity, hypertension, obesity, hyperlipidemia, insulin resistance, immunopathogenesis, vascular endothelial cells (VEC), Chlamydia pneumoniae, cytomegalovirus, heat shock protein 60 (Hsp 60), chemokines, prostacyclin PGI2, adrenomedullin, granulopoiesis, immunogens, metalloproteinases, phosphorylation, eNOS protein, adipocytes, lymphocytes, fibroblasts, adipokines, monocytes
Abstract: Cardiovascular disease is the main cause of death in the United States. Although it is recognized that moderate intensity long-term exercise can decrease the chances of dying from cardiovascular disease by favorably modifying risk factors such as hypertension, obesity, hyperlipidemia, and insulin resistance, physical activity also enhances longevity by mechanisms independent of these risk factors. This review briefly summarizes what is known about the inflammatory nature of atherosclerosis and how long-term aerobic exercise can reduce the atherogenic activity of endothelial cells, blood mononuclear cells, and adipose tissue.
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Cite this article as:
Kelly Smith J., Exercise and Cardiovascular Disease, Cardiovascular & Hematological Disorders-Drug Targets 2010; 10 (4) . https://dx.doi.org/10.2174/187152910793743823
DOI https://dx.doi.org/10.2174/187152910793743823 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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