Abstract
The intermolecular radical addition to the carbon atom of imine derivatives has received much less attention until recently, although the use of radical reaction in organic synthesis has continued to increase. This review highlights the intermolecular carbon-carbon bond forming reactions based on carbon radical addition to the carbon-nitrogen double bond. Particularly, the radical reactions of oxime ethers, hydrazones, sulfonylimines, ketimines, and so on are summarized. In this review, strategies for diastereo- and enantioselective radical reactions of imine derivatives are also summarized.
Keywords: Radical, imine, oxime ether, hydrazone, sulfonylimine, amine, diastereoselective, enantioselective
Current Organic Chemistry
Title: Progress in Intermolecular Carbon Radical Addition to Imine Derivatives
Volume: 14 Issue: 12
Author(s): Hideto Miyabe, Eito Yoshioka and Shigeru Kohtani
Affiliation:
Keywords: Radical, imine, oxime ether, hydrazone, sulfonylimine, amine, diastereoselective, enantioselective
Abstract: The intermolecular radical addition to the carbon atom of imine derivatives has received much less attention until recently, although the use of radical reaction in organic synthesis has continued to increase. This review highlights the intermolecular carbon-carbon bond forming reactions based on carbon radical addition to the carbon-nitrogen double bond. Particularly, the radical reactions of oxime ethers, hydrazones, sulfonylimines, ketimines, and so on are summarized. In this review, strategies for diastereo- and enantioselective radical reactions of imine derivatives are also summarized.
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Cite this article as:
Miyabe Hideto, Yoshioka Eito and Kohtani Shigeru, Progress in Intermolecular Carbon Radical Addition to Imine Derivatives, Current Organic Chemistry 2010; 14 (12) . https://dx.doi.org/10.2174/138527210791330477
DOI https://dx.doi.org/10.2174/138527210791330477 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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