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Combinatorial Chemistry & High Throughput Screening


ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

The Combinatorial Synthesis of Bioactive Quinoxalines, Quinoxalinones and Quinoxalinols

Author(s): Min Lv and Hui Xu

Volume 13, Issue 3, 2010

Page: [293 - 301] Pages: 9

DOI: 10.2174/138620710790980513

Price: $65


In the family of biologically active heterocyclic templates, quinoxalines, quinoxalinones, and quinoxalinols have received much attention owing to a wide range of their biological activities. As a consequence, approaches to the combinatorial synthesis of these compounds were surveyed, and this review discusses the solid-phase, solution-phase, solvent-free, and microwave-assisted parallel synthesis of quinoxalines, quinoxalinones, and quinoxalinols.

Keywords: Quinoxaline, quinoxalinone, quinoxalinol, heterocycle, solid-phase, solution-phase, solvent-free, microwave irradiation

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