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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Naturally Occurring δ-Hydroxy-γ-Lactones: Muricatacins and Related Compounds

Author(s): M. Carmen Murcia, Cristina Navarro, Ana Moreno and Aurelio G. Csaky

Volume 14, Issue 1, 2010

Page: [15 - 47] Pages: 33

DOI: 10.2174/138527210790226410

Price: $65


In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.

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