Abstract
Prosthetic valve endocarditis (PVE) is a grave medical entity with potentially fatal end results. The disease encompasses a rather small but, in the same time, vital part of IE incidents that is probable to be augmented in future years. PVE occurs in 1-4% of valve recipients during the first year following valve replacement, and in approximately 1 % per year afterwards. The type of prosthetic valve (mechanical versus bioprosthetic) seems not having an impact on the rate of development of IE and it is comparable in both groups (0.8 cases per year of follow-up). The pathogenetic mechanisms, pathogens implicated, clinical features and diagnostic approach of PVE will be reviewed here, along with the antibacterial and potential surgical treatment and prevention of the disease.
Cardiovascular & Hematological Disorders-Drug Targets
Title: Prosthetic Valve Endocarditis: Diagnostic Approach and Treatment Options
Volume: 9 Issue: 4
Author(s): Ioannis Starakis and Elias E. Mazokopakis
Affiliation:
- Department of Internal Medicine, Patras University Hospital, 26500 Rion, Patras, Greece.,Greece
Abstract: Prosthetic valve endocarditis (PVE) is a grave medical entity with potentially fatal end results. The disease encompasses a rather small but, in the same time, vital part of IE incidents that is probable to be augmented in future years. PVE occurs in 1-4% of valve recipients during the first year following valve replacement, and in approximately 1 % per year afterwards. The type of prosthetic valve (mechanical versus bioprosthetic) seems not having an impact on the rate of development of IE and it is comparable in both groups (0.8 cases per year of follow-up). The pathogenetic mechanisms, pathogens implicated, clinical features and diagnostic approach of PVE will be reviewed here, along with the antibacterial and potential surgical treatment and prevention of the disease.
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Cite this article as:
Starakis Ioannis and Mazokopakis E. Elias, Prosthetic Valve Endocarditis: Diagnostic Approach and Treatment Options, Cardiovascular & Hematological Disorders-Drug Targets 2009; 9(4) . https://dx.doi.org/10.2174/1871529X10909040249
DOI https://dx.doi.org/10.2174/1871529X10909040249 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |

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