Generic placeholder image

Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

A Synthetic Approach and Antimicrobial Evaluation of Annulated Pyrimidine and Triazine Derivatives

Author(s): A. A. Aly

Volume 13, Issue 17, 2009

Page: [1758 - 1764] Pages: 7

DOI: 10.2174/138527209789578090

Price: $65


A smooth and rapid one step synthesis of novel pyrido[2,3:3,4]pyrazolo[1,5-a]pyrimidines 4a,b and 7, pyrido[2,3:3,4]pyrazolo[5,1-c]triazines10-12a,b, pyrido[3“,2“:4,5]thieno[3,2:4,5]pyrimido/triazino[1,6-a]benzimidazoles 15-20 in synthetically useful yields utilizing, 3-amino-4-phenyl-5-(saccharin-2-yl)-1H-pyrazolo[3,4-b]pyridine (3) were described. The structure assignment of the new compounds is based on chemical and spectroscopic evidence. Preliminary biological studies of some synthesized compounds showed promising antimicrobial activities.

« Previous

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy