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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Recent Advance in Asymmetric Alkynylation of Ketones

Author(s): Li Lin and Rui Wang

Volume 13, Issue 15, 2009

Page: [1565 - 1576] Pages: 12

DOI: 10.2174/138527209789177725

Price: $65


Asymmetric alkynylation of ketones can provide versatile chiral tertiary propargylic alcohols. A series of strategies have been achieved in the past few years. Relative optimal reaction conditions for obtaining the highest enantioselectivities and yields, as well as the practical scope of different types of catalytic systems are reviewed.

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