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Current Drug Targets

Editor-in-Chief

ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

Mini-Review Article

Emerging Carbon Dots Nanomaterials for Ovarian Cancer Diagnosis and Therapy

In Press, (this is not the final "Version of Record"). Available online 04 February, 2025
Author(s): Anoop Narayanan V, Rajesh B.R.D. Yamajala, Jayachandran Venkatesan, Myung-Geol Pang and Gangaraju Gedda*
Published on: 04 February, 2025

DOI: 10.2174/0113894501347816241223065618

Price: $95

Abstract

Delayed diagnosis and limited treatment options make ovarian cancer difficult to treat. This paper examines the growing role of Carbon Dots (CDs) in ovarian cancer diagnosis and treatment. Photoluminescence and biocompatibility make CDs ideal for biomedical use. We emphasize their ability to improve fluorescence and molecular imaging in imaging and diagnostics. We also demonstrate the efficacy of carbon dots in targeted drug delivery systems in overcoming drug resistance and improving therapeutic outcomes. Photodynamic and photothermal therapies are used to show that CDs can treat hypoxic ovarian cancer tumours. We also discuss CD safety issues and constraints, emphasising the need for thorough assessments and fine-tuning. Future research focuses on personalised medicine and CD integration with other therapies. This text concludes by discussing CDs' clinical use and the challenges of production and regulatory approval. CDs can improve ovarian cancer diagnosis and treatment, improving patient outcomes and survival.

Keywords: Carbon dot, ovarian cancer, diagnosis, targeted drug delivery, photodynamic therapy, photoluminescence


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