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Current Drug Delivery

Editor-in-Chief

ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

Review Article

Recent Advances in Nanotherapeutics and Theranostics for Squamous Cell Carcinoma: A Comprehensive Review

In Press, (this is not the final "Version of Record"). Available online 24 January, 2025
Author(s): Neeraj Sharma, ABHIRAM KUMAR*, Sharda Sambhakar, Daksh Bhatia, Sahil Hussain, Mohd Mursal, Bishambar Singh and Kumar Pranav Narayan
Published on: 24 January, 2025

DOI: 10.2174/0115672018342513241230061704

Price: $95

Abstract

Recent advancements in nanotherapeutics have revolutionized cancer treatment through the integration of diagnostic and therapeutic modalities, known as theranostics. This critical review examines the current landscape of nanotherapeutics for various cancers, such as bladder and head and neck squamous cell carcinoma, highlighting current advancements in nanotherapeutics and challenges. Key approaches discussed include biomimetic smart nanocarriers, polymeric smart nanocarriers, inorganic-based smart nanocarriers, and nanorobots. Furthermore, diverse nanomaterials have been explored in theranostics, including liposomes, polymeric nanoparticles, and inorganic nanoparticles such as quantum dots and mesoporous silica nanoparticles. Furthermore, the integration of imaging techniques such as surface-enhanced Raman scattering (SERS) and positron emission tomography (PET) with therapeutic nanoparticles has been analyzed for potential clinical applications.

Keywords: Head and neck cancer, bladder cancer, Squamous cell carcinoma, nanotherapeutics, theranostics, smart biomaterial, Drug delivery.


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