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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Potential Mechanisms of Covid-19 Related Nervous System Damage and Effects on Female Fertility

In Press, (this is not the final "Version of Record"). Available online 24 October, 2024
Author(s): Chen-yue Qian, Si-ning Hu, Liu Huadong and Jing-jin Liu*
Published on: 24 October, 2024

DOI: 10.2174/0109298673333968241011092801

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Abstract

Signs and symptoms that persist or worsen beyond the “acute COVID-19” stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.

Keywords: COVID-19, central nervous system, immune response, fertility, pharmacological treatment.


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