Abstract
Signs and symptoms that persist or worsen beyond the “acute COVID-19” stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.
Keywords: COVID-19, central nervous system, immune response, fertility, pharmacological treatment.
Current Medicinal Chemistry
Title:Potential Mechanisms of Covid-19 Related Nervous System Damage and Effects on Female Fertility
Volume: 32
Author(s): Chen-yue Qian, Si-ning Hu, Liu Huadong and Jing-jin Liu*
Affiliation:
- The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
- Department of Cardiology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China
- Department of Cardiology, Shenzhen Cardiovascular Minimally Invasive Medical Engineering Technology Research and Development Center, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China
- Shenzhen Key Laboratory of Stem Cell Research and Clinical Transformation, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China
- Department of Geriatrics, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China
Keywords: COVID-19, central nervous system, immune response, fertility, pharmacological treatment.
Abstract: Signs and symptoms that persist or worsen beyond the “acute COVID-19” stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.
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Cite this article as:
Qian Chen-yue, Hu Si-ning, Huadong Liu and Liu Jing-jin*, Potential Mechanisms of Covid-19 Related Nervous System Damage and Effects on Female Fertility, Current Medicinal Chemistry 2025; 32 () . https://dx.doi.org/10.2174/0109298673333968241011092801
DOI https://dx.doi.org/10.2174/0109298673333968241011092801 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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